Scientific Publication

Chicken IFN Kappa: A Novel Cytokine with Antiviral Activities

author(s) Santhakumar, D. - Iqbal, M. - Nair, V. - Munir, M.
from UK Foreign, Commonwealth & Development Office (FCDO)
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themes
regions
  • South-Eastern Asia
  • Asia
  • World
  • Southern Asia
citation

Santhakumar D, Iqbal M, Nair V, Munir M. (2017). Chicken IFN Kappa: A Novel Cytokine with Antiviral Activities. Sci Rep. 7(1): 2719

Publications and datasets provided via GARDIAN

Abstract

Interferons (IFNs) are essential components of the host innate immune system and define first-line of defence against pathogens. In mammals, several type I IFNs are identified, however, only limited data is available on the repertoire of IFNs in avian species. Here we report the characterization of chicken IFN-κ (chIFN-κ) near the type I IFN locus on the sex-determining Z chromosome. This work arises from the Zoonoses and Emerging Livestock Systems (ZELS) programme

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